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Elevating SOX2 in prostate tumor cells upregulates expression of neuroendocrine genes, but does not reduce the inhibitory effects of enzalutamide

Prostate cancer (PCa) is one of the leading causes of cancer deaths in men. In this cancer, the stem cell transcription factor SOX2 increases during tumor progression, especially as the cancer progresses to the highly aggressive neuroendocrine-like phenotype. Other studies have shown that knockdown...

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Bibliografski detalji
Izdano u:J Cell Physiol
Glavni autori: Metz, Ethan P., Wilder, Phillip J., Dong, Jixin, Datta, Kaustubh, Rizzino, Angie
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961844/
https://ncbi.nlm.nih.gov/pubmed/31587305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.29267
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