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Metformin prevents the development of oral squamous cell carcinomas from carcinogen-induced premalignant lesions
Head and neck squamous cell carcinoma (HNSCC) is a major public health concern. The recent identification of the mammalian Target of Rapamycin Complex 1 (mTORC1) signaling pathway as a highly prevalent molecular signature underlying HNSCC pathogenesis has provided the foundation to search for novel...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429367/ https://ncbi.nlm.nih.gov/pubmed/22467081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0502 |
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