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Metformin prevents the development of oral squamous cell carcinomas from carcinogen-induced premalignant lesions

Head and neck squamous cell carcinoma (HNSCC) is a major public health concern. The recent identification of the mammalian Target of Rapamycin Complex 1 (mTORC1) signaling pathway as a highly prevalent molecular signature underlying HNSCC pathogenesis has provided the foundation to search for novel...

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Detalhes bibliográficos
Main Authors: Vitale-Cross, Lynn, Molinolo, Alfredo A., Martin, Daniel, Younis, Rania H., Maruyama, Takashi, Patel, Vyomesh, Chen, Wanjun, Schneider, Abraham, Gutkind, J. Silvio
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429367/
https://ncbi.nlm.nih.gov/pubmed/22467081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0502
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