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Complementary Chimeric Isoforms Reveal Dscam1 Binding Specificity in Vivo

Dscam1 potentially encodes 19,008 ectodomains of a cell recognition molecule of the immunoglobulin (Ig) superfamily through alternative splicing. Each ectodomain, comprising a unique combination of three variable (Ig) domains, exhibits isoform-specific homophilic binding in vitro. Although we have p...

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Bibliografski detalji
Glavni autori: Wu, Wei, Ahlsen, Goran, Baker, David, Shapiro, Lawrence, Zipursky, S. Lawrence
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429342/
https://ncbi.nlm.nih.gov/pubmed/22542180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.02.029
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