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Detection of early Abl kinase activation after ionizing radiation using a peptide biosensor
The ubiquitously expressed Abl protein is a non-receptor tyrosine kinase that undergoes nuclear-cytoplasmic shuttling and is involved in many signalling pathways in the cell. Nuclear Abl is activated by DNA damage to regulate DNA repair, cell cycle checkpoints and apoptosis. Previous studies have es...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429332/ https://ncbi.nlm.nih.gov/pubmed/22334513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201100763 |
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