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Aberrant expression of IL-22 receptor 1 (IL-22R1) and autocrine IL-22 stimulation contribute to tumorigenicity in ALK-positive anaplastic large cell lymphoma

One of the characteristic features of anaplastic lymphoma kinase (ALK)-positive, anaplastic large cell lymphoma (ALK(+)ALCL) is the constitutive activation of STAT3, a defect believed to be important for the pathogenesis of these tumors. In this report, we describe the existence of an autocrine stim...

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Detalhes bibliográficos
Main Authors: Bard, Jennifer Dien, Gelebart, Pascal, Anand, Mona, Amin, Hesham M., Lai, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429118/
https://ncbi.nlm.nih.gov/pubmed/18509351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2008.129
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