IL-21 Contributes to JAK3/STAT3 Activation and Promotes Cell Growth in ALK-Positive Anaplastic Large Cell Lymphoma

Interleukin (IL)-21 has been reported to both stimulate cell growth and promote survival in benign lymphoid cells and several types of hematopoietic neoplasms. It induces JAK3/STAT3 signaling, a biologically important cellular pathway activated in most cases of anaplastic lymphoma kinase (ALK)-expre...

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Detalhes bibliográficos
Main Authors: Dien Bard, Jennifer, Gelebart, Pascal, Anand, Mona, Zak, Zoulika, Hegazy, Samar A., Amin, Hesham M., Lai, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716977/
https://ncbi.nlm.nih.gov/pubmed/19608866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080982
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