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A role for apoptosis-inducing factor in T cell development
Apoptosis-inducing factor (Aif) is a mitochondrial flavoprotein that regulates cell metabolism and survival in many tissues. We report that aif-hypomorphic harlequin (Hq) mice show thymic hypocellularity and a cell-autonomous thymocyte developmental block associated with apoptosis at the β-selection...
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Главные авторы: | , , , , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
The Rockefeller University Press
2012
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428951/ https://ncbi.nlm.nih.gov/pubmed/22869892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110306 |
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