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Naive CD4 T cells from aged mice show enhanced death upon primary activation
Poor T cell immunity is one of the many defects seen in elderly humans and aged (Ad) mice. We report that naive CD4 T cells from aged mice (ANCD4 cells) showed greater apoptosis upon primary activation than those from young (Yg) mice, with loss of mitochondrial membrane potential, poor activation of...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2767129/ https://ncbi.nlm.nih.gov/pubmed/19748905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxp094 |
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