A role for apoptosis-inducing factor in T cell development

Apoptosis-inducing factor (Aif) is a mitochondrial flavoprotein that regulates cell metabolism and survival in many tissues. We report that aif-hypomorphic harlequin (Hq) mice show thymic hypocellularity and a cell-autonomous thymocyte developmental block associated with apoptosis at the β-selection...

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Detalhes bibliográficos
Main Authors: Banerjee, Hridesh, Das, Abhishek, Srivastava, Smita, Mattoo, Hamid R., Thyagarajan, Krishnamurthy, Khalsa, Jasneet Kaur, Tanwar, Shalini, Das, Deepika Sharma, Majumdar, Subeer S., George, Anna, Bal, Vineeta, Durdik, Jeannine M., Rath, Satyajit
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428951/
https://ncbi.nlm.nih.gov/pubmed/22869892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110306
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