IL-1R–MyD88 signaling in keratinocyte transformation and carcinogenesis

Constitutively active RAS plays a central role in the development of human cancer and is sufficient to induce tumors in two-stage skin carcinogenesis. RAS-mediated tumor formation is commonly associated with up-regulation of cytokines and chemokines that mediate an inflammatory response considered r...

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Autors principals: Cataisson, Christophe, Salcedo, Rosalba, Hakim, Shakeeb, Moffitt, B. Andrea, Wright, Lisa, Yi, Ming, Stephens, Robert, Dai, Ren-Ming, Lyakh, Lyudmila, Schenten, Dominik, Yuspa, H. Stuart, Trinchieri, Giorgio
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428947/
https://ncbi.nlm.nih.gov/pubmed/22908325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101355
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