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IL-1R–MyD88 signaling in keratinocyte transformation and carcinogenesis
Constitutively active RAS plays a central role in the development of human cancer and is sufficient to induce tumors in two-stage skin carcinogenesis. RAS-mediated tumor formation is commonly associated with up-regulation of cytokines and chemokines that mediate an inflammatory response considered r...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428947/ https://ncbi.nlm.nih.gov/pubmed/22908325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101355 |
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