MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18

Signaling through the adaptor protein myeloid differentiation factor 88 (MyD88) promotes carcinogenesis in several cancer models. In contrast, MyD88 signaling has a protective role in the development of azoxymethane (AOM)/dextran sodium sulfate (DSS) colitis-associated cancer (CAC). The inability of...

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Main Authors: Salcedo, Rosalba, Worschech, Andrea, Cardone, Marco, Jones, Yava, Gyulai, Zsofia, Dai, Ren-Ming, Wang, Ena, Ma, Winnie, Haines, Diana, O'hUigin, Colm, Marincola, Francesco M., Trinchieri, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916129/
https://ncbi.nlm.nih.gov/pubmed/20624890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100199
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