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BubR1 is required for prophase I arrest and prometaphase progression during female meiosis I
Two critical stages of mammalian oocyte regulation are prophase I arrest, which is important for sustaining the oocyte pool, and meiosis I (MI), which produces fertilisable eggs. Here we find that the spindle assembly checkpoint protein, BubR1, regulates both stages in mouse oocytes. We show that oo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428834/ https://ncbi.nlm.nih.gov/pubmed/19965510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175326 |
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