Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins

The Muscleblind-like (Mbnl) family of RNA binding proteins plays important roles in muscle and eye development and in Myotonic Dystrophy (DM), where expanded CUG or CCUG repeats functionally deplete Mbnl proteins. We identified transcriptome-wide functional and biophysical targets of Mbnl proteins i...

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書誌詳細
主要な著者: Wang, Eric T., Cody, Neal A. L., Jog, Sonali, Biancolella, Michela, Wang, Thomas T., Treacy, Daniel J., Luo, Shujun, Schroth, Gary P., Housman, David E., Reddy, Sita, Lécuyer, Eric, Burge, Christopher B.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428802/
https://ncbi.nlm.nih.gov/pubmed/22901804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.041
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