A systematic comparison and evaluation of high density exon arrays and RNA-seq technology used to unravel the peripheral blood transcriptome of sickle cell disease

BACKGROUND: Transcriptomic studies in clinical research are essential tools for deciphering the functional elements of the genome and unraveling underlying disease mechanisms. Various technologies have been developed to deduce and quantify the transcriptome including hybridization and sequencing-bas...

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Main Authors: Raghavachari, Nalini, Barb, Jennifer, Yang, Yanqin, Liu, Poching, Woodhouse, Kimberly, Levy, Daniel, O‘Donnell, Christopher J, Munson, Peter J, Kato, Gregory J
格式: Artigo
語言:Inglês
出版: BioMed Central 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428653/
https://ncbi.nlm.nih.gov/pubmed/22747986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-5-28
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