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Transcriptome profiling and sequencing of differentiated human hematopoietic stem cells reveal lineage-specific expression and alternative splicing of genes

Hematopoietic differentiation is strictly regulated by complex network of transcription factors that are controlled by ligands binding to cell surface receptors. Disruptions of the intricate sequences of transcriptional activation and suppression of multiple genes cause hematological diseases, such...

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Main Authors: Liu, Poching, Barb, Jennifer, Woodhouse, Kimberly, Taylor, James G., Munson, Peter J., Raghavachari, Nalini
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217327/
https://ncbi.nlm.nih.gov/pubmed/21828245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00099.2011
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