A systematic comparison and evaluation of high density exon arrays and RNA-seq technology used to unravel the peripheral blood transcriptome of sickle cell disease

BACKGROUND: Transcriptomic studies in clinical research are essential tools for deciphering the functional elements of the genome and unraveling underlying disease mechanisms. Various technologies have been developed to deduce and quantify the transcriptome including hybridization and sequencing-bas...

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Main Authors: Raghavachari, Nalini, Barb, Jennifer, Yang, Yanqin, Liu, Poching, Woodhouse, Kimberly, Levy, Daniel, O‘Donnell, Christopher J, Munson, Peter J, Kato, Gregory J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428653/
https://ncbi.nlm.nih.gov/pubmed/22747986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-5-28
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