A systematic comparison and evaluation of high density exon arrays and RNA-seq technology used to unravel the peripheral blood transcriptome of sickle cell disease

BACKGROUND: Transcriptomic studies in clinical research are essential tools for deciphering the functional elements of the genome and unraveling underlying disease mechanisms. Various technologies have been developed to deduce and quantify the transcriptome including hybridization and sequencing-bas...

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Autori principali: Raghavachari, Nalini, Barb, Jennifer, Yang, Yanqin, Liu, Poching, Woodhouse, Kimberly, Levy, Daniel, O‘Donnell, Christopher J, Munson, Peter J, Kato, Gregory J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428653/
https://ncbi.nlm.nih.gov/pubmed/22747986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-5-28
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