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Sepsis-Induced Cardiac Mitochondrial Dysfunction Involves Altered Mitochondrial-Localization of Tyrosine Kinase Src and Tyrosine Phosphatase SHP2

Our previous research demonstrated that sepsis produces mitochondrial dysfunction with increased mitochondrial oxidative stress in the heart. The present study investigated the role of mitochondria-localized signaling molecules, tyrosine kinase Src and tyrosine phosphatase SHP2, in sepsis-induced ca...

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Autors principals: Zang, Qun S., Martinez, Bobbie, Yao, Xiao, Maass, David L., Ma, Lisha, Wolf, Steven E., Minei, Joseph P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428365/
https://ncbi.nlm.nih.gov/pubmed/22952679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043424
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