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Tyrosine phosphatases such as SHP-2 act in a balance with Src-family kinases in stabilization of postsynaptic clusters of acetylcholine receptors

BACKGROUND: Development of neural networks requires that synapses are formed, eliminated and stabilized. At the neuromuscular junction (NMJ), agrin/MuSK signaling, by triggering downstream pathways, causes clustering and phosphorylation of postsynaptic acetylcholine receptors (AChRs). Postnatally, A...

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Detaylı Bibliyografya
Asıl Yazarlar: Camilleri, Alain A, Willmann, Raffaella, Sadasivam, Gayathri, Lin, Shuo, Rüegg, Markus A, Gesemann, Matthias, Fuhrer, Christian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924855/
https://ncbi.nlm.nih.gov/pubmed/17605785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-8-46
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