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The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters

BACKGROUND: A crucial event in the development of the vertebrate neuromuscular junction (NMJ) is the postsynaptic enrichment of muscle acetylcholine (ACh) receptors (AChRs). This process involves two distinct steps: the local clustering of AChRs at synapses, which depends on the activation of the mu...

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Autors principals: Qian, Yueping K, Chan, Ariel WS, Madhavan, Raghavan, Peng, H Benjamin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490698/
https://ncbi.nlm.nih.gov/pubmed/18647419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-9-70
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