Biochemical and Functional Studies of Lymphoid-Specific Tyrosine Phosphatase (Lyp) Variants S201F and R266W

The Lymphoid specific tyrosine phosphatase (Lyp) has elicited tremendous research interest due to the high risk of its missense mutation R620W in a wide spectrum of autoimmune diseases. While initially characterized as a gain-of-function mutant, R620W was thought to lead to autoimmune diseases throu...

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Main Authors: Liu, Jing, Chen, Ming, Li, Rong, Yang, Fan, Shi, Xuanren, Zhu, Lichao, Wang, Hong-Mei, Yao, Wei, Liu, Qiji, Meng, Fan-Guo, Sun, Jin-Peng, Pang, Qi, Yu, Xiao
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428364/
https://ncbi.nlm.nih.gov/pubmed/22952725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043631
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