Identification of a variant form of tyrosine phosphatase LYP

BACKGROUND: Protein tyrosine phosphatases (PTPs) are important cell signaling regulators with major pathological implications. LYP (also known as PTPN22) is an intracellular enzyme initially found to be predominately expressed in lymphocytes. Importantly, an allelic R620W variant of LYP is strongly...

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Main Authors: Wang, Shaofeng, Dong, Hongbo, Han, Jiayu, Ho, Wanting T, Fu, Xueqi, Zhao, Zhizhuang J
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987843/
https://ncbi.nlm.nih.gov/pubmed/21044313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-11-78
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