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Reduced Expression of UGT1A1 in Intestines of Humanized UGT1 Mice via Inactivation of NF-κB Leads to Hyperbilirubinemia

BACKGROUND & AIMS: Bilirubin is a natural and potent antioxidant that accumulates in the blood of newborn children and leads to physiological jaundice. Breast-fed infants have higher serum levels of bilirubin than formula-fed infants and are at risk for bilirubin-induced neurological dysfunction...

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Autori principali: FUJIWARA, RYOICHI, CHEN, SHUJUAN, KARIN, MICHAEL, TUKEY, ROBERT H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428231/
https://ncbi.nlm.nih.gov/pubmed/21983082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.09.045
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