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Aneuploidy as a mechanism for stress-induced liver adaptation
Over half of the mature hepatocytes in mice and humans are aneuploid and yet retain full ability to undergo mitosis. This observation has raised the question of whether this unusual somatic genetic variation evolved as an adaptive mechanism in response to hepatic injury. According to this model, hep...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428097/ https://ncbi.nlm.nih.gov/pubmed/22863619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64026 |
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