C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice

The myeloid-specific transcription factor, CCAAT/enhancer-binding protein ε (C/EBPε) is a critical mediator of myelopoiesis. Mutation of this gene is responsible for neutrophil-specific granule deficiency in humans, a condition that confers susceptibility to Staphylococcus aureus infection. We found...

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Main Authors: Kyme, Pierre, Thoennissen, Nils H., Tseng, Ching Wen, Thoennissen, Gabriela B., Wolf, Andrea J., Shimada, Kenichi, Krug, Utz O., Lee, Kunik, Müller-Tidow, Carsten, Berdel, Wolfgang E., Hardy, W. David, Gombart, Adrian F., Koeffler, H. Phillip, Liu, George Y.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428083/
https://ncbi.nlm.nih.gov/pubmed/22922257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62070
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