Glucocorticoid-Induced Tumor Necrosis Factor Receptor Family-Related Protein Regulates CD4(+) T Cell-Mediated Colitis in Mice

BACKGROUND & AIMS: The glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR; also called TNFRSF18 or CD357) regulates the T-cell mediated immune response and is present on surfaces of T regulatory (Treg) and activated CD4(+) T cells. We investigated the roles of GIT...

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Bibliografiske detaljer
Main Authors: Liao, Gongxian, Detre, Cynthia, Berger, Scott B., Engel, Pablo, de Waal Malefyt, Rene, Herzog, Roland W., Bhan, Atul K., Terhorst, Cox
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428052/
https://ncbi.nlm.nih.gov/pubmed/22155173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.11.031
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