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Interplay between FOXO, TOR, and Akt
FOXO transcription factors have emerged as rheostats that coordinate the activities of Akt and target of rapamycin complexes (TORCs). This review summarizes the regulatory circuits mediated by the activation of FOXO, which in turn modulate Akt and TORCs activities. The biological significance of the...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427795/ https://ncbi.nlm.nih.gov/pubmed/21440577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.03.013 |
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