Synthesis and Biological Properties of C-2 Triazolylinosine Derivatives

[Image: see text] O(6)-(Benzotriazol-1H-yl)guanosine and its 2′-deoxy analogue are readily converted to the O(6)-allyl derivatives that upon diazotization with t-BuONO and TMS-N(3) yield the C-2 azido derivatives. We have previously analyzed the solvent-dependent azide•tetrazole equilibrium of C-6 a...

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Hauptverfasser: Lakshman, Mahesh K., Kumar, Amit, Balachandran, Raghavan, Day, Billy W., Andrei, Graciela, Snoeck, Robert, Balzarini, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427785/
https://ncbi.nlm.nih.gov/pubmed/22758929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo300628y
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