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Pregabalin Suppresses Spinal Neuronal Hyperexcitability and Visceral Hypersensitivity in the Absence of Peripheral Pathophysiology

BACKGROUND: Opioid induced hyperalgesia is recognised in the laboratory and the clinic, generating central hyperexcitability in the absence of peripheral pathology. We investigated pregabalin, indicated for neuropathic pain, and ondansetron, a drug that disrupts descending serotonergic processing in...

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書誌詳細
主要な著者: Bannister, Kirsty, Sikandar, Shafaq, Bauer, Claudia S., Dolphin, Annette C., Porreca, Frank, Dickenson, Anthony H.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427727/
https://ncbi.nlm.nih.gov/pubmed/21602662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31821f6545
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