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Unmasking the tonic-aversive state in neuropathic pain

Tonic pain has been difficult to demonstrate in animals. Because relief of pain is rewarding, analgesic agents that are not rewarding in the absence of pain should become rewarding only when there is ongoing pain. We used conditioned place preference to concomitantly determine the presence of tonic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: King, Tamara, Vera-Portocarrero, Louis, Gutierrez, Tannia, Vanderah, Todd W, Dussor, Gregory, Lai, Josephine, Fields, Howard L, Porreca, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427725/
https://ncbi.nlm.nih.gov/pubmed/19783992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2407
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