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Unmasking the tonic-aversive state in neuropathic pain

Tonic pain has been difficult to demonstrate in animals. Because relief of pain is rewarding, analgesic agents that are not rewarding in the absence of pain should become rewarding only when there is ongoing pain. We used conditioned place preference to concomitantly determine the presence of tonic...

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Autors principals: King, Tamara, Vera-Portocarrero, Louis, Gutierrez, Tannia, Vanderah, Todd W, Dussor, Gregory, Lai, Josephine, Fields, Howard L, Porreca, Frank
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427725/
https://ncbi.nlm.nih.gov/pubmed/19783992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2407
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