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Unmasking the tonic-aversive state in neuropathic pain

Tonic pain has been difficult to demonstrate in animals. Because relief of pain is rewarding, analgesic agents that are not rewarding in the absence of pain should become rewarding only when there is ongoing pain. We used conditioned place preference to concomitantly determine the presence of tonic...

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Detalhes bibliográficos
Main Authors: King, Tamara, Vera-Portocarrero, Louis, Gutierrez, Tannia, Vanderah, Todd W, Dussor, Gregory, Lai, Josephine, Fields, Howard L, Porreca, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427725/
https://ncbi.nlm.nih.gov/pubmed/19783992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2407
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