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Effect of SkM1 Sodium Channels Delivered Via a Cell Platform on Cardiac Conduction and Arrhythmia Induction

BACKGROUND: In depolarized myocardial infarct epicardial border zones (EBZ), the cardiac sodium channel is largely inactivated, contributing to slow conduction and reentry. We have demonstrated that adenoviral delivery of the skeletal muscle sodium channel SkM1 to EBZ normalizes conduction and reduc...

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Detalhes bibliográficos
Main Authors: Boink, Gerard J.J., Lu, Jia, Driessen, Helen E., Duan, Lian, Sosunov, Eugene A., Anyukhovsky, Evgeny P., Shlapakova, Iryna N., Lau, David H., Rosen, Tove S., Danilo, Peter, Jia, Zhiheng, Ozgen, Nazira, Bobkov, Yevgeniy, Guo, Yuanjian, Brink, Peter R., Kryukova, Yelena, Robinson, Richard B., Entcheva, Emilia, Cohen, Ira S., Rosen, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427660/
https://ncbi.nlm.nih.gov/pubmed/22722661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.111.969907
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