Nicotine/Cigarette-smoke Promotes Metastasis of Pancreatic Cancer Through α7nAChR-mediated MUC4 Up-regulation

Despite evidence that long-term smoking is the leading risk factor for pancreatic malignancies, the underlying mechanism(s) for cigarette-smoke (CS)-induced pancreatic cancer (PC) pathogenesis has not been well-established. Our previous studies revealed an aberrant expression of the MUC4 mucin in PC...

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Hauptverfasser: Momi, Navneet, Ponnusamy, Moorthy P., Kaur, Sukhwinder, Rachagani, Satyanarayana, Kunigal, Sateesh S, Chellappan, Srikumar, Ouellette, Michel M, Batra, Surinder K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427417/
https://ncbi.nlm.nih.gov/pubmed/22614008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.163
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