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Both Lethal and Edema Toxins of Bacillus anthracis Disrupt the Human Dendritic Cell Chemokine Network

Bacillus anthracis, the agent of anthrax, produces two main virulence factors: a capsule and two toxins. Both lethal toxin (LT) and edema toxin (ET) paralyze the immune defense system. Here, we analyze the effects of LT and ET on the capacity of human monocyte-derived dendritic cells (MoDC) to produ...

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Detalhes bibliográficos
Main Authors: Cleret-Buhot, Aurélie, Mathieu, Jacques, Tournier, Jean-Nicolas, Quesnel-Hellmann, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427382/
https://ncbi.nlm.nih.gov/pubmed/22937027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043266
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