Both Lethal and Edema Toxins of Bacillus anthracis Disrupt the Human Dendritic Cell Chemokine Network

Bacillus anthracis, the agent of anthrax, produces two main virulence factors: a capsule and two toxins. Both lethal toxin (LT) and edema toxin (ET) paralyze the immune defense system. Here, we analyze the effects of LT and ET on the capacity of human monocyte-derived dendritic cells (MoDC) to produ...

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Bibliografiske detaljer
Main Authors: Cleret-Buhot, Aurélie, Mathieu, Jacques, Tournier, Jean-Nicolas, Quesnel-Hellmann, Anne
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427382/
https://ncbi.nlm.nih.gov/pubmed/22937027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043266
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