Technical and Regulatory Shortcomings of the TaqMan Version 1 HIV Viral Load Assay

BACKGROUND: The lower limit of detection of the original Roche Amplicor HIV plasma viral load (pVL) assay (50 copies/mL) has defined HIV treatment success. The Amplicor assay, however, has been replaced by the Roche TaqMan assay(s). Changes to the limits of detection and calibration have not been va...

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Detalhes bibliográficos
Main Authors: Brumme, Chanson J., Swenson, Luke C., Wynhoven, Brian, Yip, Benita, Skinner, Stuart, Lima, Viviane Dias, Montaner, Julio S. G., Harrigan, P. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427308/
https://ncbi.nlm.nih.gov/pubmed/22937116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043882
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