The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas

Genetic alterations of 16q21-q22, the locus of a 6-cadherin cluster, are frequently involved in multiple tumors, suggesting the presence of critical tumor suppressor genes (TSGs). Using 1 Mb array comparative genomic hybridization (aCGH), we refined a small hemizygous deletion (∼1 Mb) at 16q21-22.1,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, L, Ying, J, Li, H, Zhang, Y, Shu, X, Fan, Y, Tan, J, Cao, Y, Tsao, S W, Srivastava, G, Chan, A T C, Tao, Q
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2012
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426851/
https://ncbi.nlm.nih.gov/pubmed/22139084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.541
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