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Lipoic Acid Metabolism of Plasmodium - A Suitable Drug Target

α-Lipoic acid (6,8-thioctic acid; LA) is a vital co-factor of α-ketoacid dehydrogenase complexes and the glycine cleavage system. In recent years it was shown that biosynthesis and salvage of LA in Plasmodium are necessary for the parasites to complete their complex life cycle. LA salvage requires t...

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Autors principals: Storm, Janet, Müller, Sylke
Format: Artigo
Idioma:Inglês
Publicat: Bentham Science Publishers 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426790/
https://ncbi.nlm.nih.gov/pubmed/22607141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138161212801327266
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