Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development

BACKGROUND: Plasmodium falciparum contains three genes encoding potential glutamate dehydrogenases. The protein encoded by gdha has previously been biochemically and structurally characterized. It was suggested that it is important for the supply of reducing equivalents during intra-erythrocytic dev...

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Dettagli Bibliografici
Autori principali: Storm, Janet, Perner, Jan, Aparicio, Isabela, Patzewitz, Eva-Maria, Olszewski, Kellen, Llinas, Manuel, Engel, Paul C, Müller, Sylke
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163627/
https://ncbi.nlm.nih.gov/pubmed/21756354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-193
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