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Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development

BACKGROUND: Plasmodium falciparum contains three genes encoding potential glutamate dehydrogenases. The protein encoded by gdha has previously been biochemically and structurally characterized. It was suggested that it is important for the supply of reducing equivalents during intra-erythrocytic dev...

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Autors principals: Storm, Janet, Perner, Jan, Aparicio, Isabela, Patzewitz, Eva-Maria, Olszewski, Kellen, Llinas, Manuel, Engel, Paul C, Müller, Sylke
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163627/
https://ncbi.nlm.nih.gov/pubmed/21756354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-193
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