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Renaturation kinetics and thermal stability of DNA in aqueous solutions of formamide and urea.
This paper reports the results of a systematic study of the effects of formamide and urea on the thermal stability and renaturation kinetics of DNA. Increasing concentrations of urea in the range 0 to 8 molar lower the Tm by 2.25 degrees C per molar, and decreases the renaturation rate by approximat...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1977
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC342670/ https://ncbi.nlm.nih.gov/pubmed/928068 |
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