Thermodynamic effects of formamide on DNA stability.

Formamide lowers melting temperatures (Tm) of DNAs linearly by 2.4-2.9 degrees C/mole of formamide (C(F)) depending on the (G+C) composition, helix conformation and state of hydration. The inherent cooperativity of melting is unaffected by the denaturant. dTm/dC(F)for 11 plasmid domains of 0.23 < (G...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Blake, R D, Delcourt, S G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145899/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8668541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.11.2095
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