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The aminoglycoside multi-acetylating activity of the enhanced intracellular survival (Eis) protein from Mycobacterium smegmatis and its inhibition

The enhanced intracellular survival (Eis) protein improves Mycobacterium smegmatis (Msm) survival in macrophages and functions as the acetyltransferase responsible for kanamycin A resistance, a hallmark of extensively drug-resistant (XDR) tuberculosis, in a large number of Mycobacterium tuberculosis...

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Bibliografiske detaljer
Main Authors: Chen, Wenjing, Green, Keith D., Tsodikov, Oleg V., Garneau-Tsodikova, Sylvie
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426641/
https://ncbi.nlm.nih.gov/pubmed/22646013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3004473
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