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Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis

Each year, millions of people worldwide contract tuberculosis (TB), the deadliest infection. The spread of infections with drug-resistant strains of Mycobacterium tuberculosis (Mtb) that are refractory to treatment poses a major global challenge. A major cause of resistance to antitubercular drugs o...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Green, Keith D., Punetha, Ankita, Hou, Caixia, Garneau-Tsodikova, Sylvie, Tsodikov, Oleg V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337102/
https://ncbi.nlm.nih.gov/pubmed/31433614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00228
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