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An Ultrasound Contrast Agent targeted to P-selectin detects Activated Platelets at Supra-arterial Shear Flow Conditions
OBJECTIVES: To evaluate targeting of a microbubble contrast agent to platelets under high shear flow using the natural selectin ligand sialyl Lewis(a). MATERIALS AND METHODS: Biotinylated polyacrylamide Sialyl Lewis(a) or biotinylated carbohydrate-free polymer (used as a control) were attached to bi...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3426507/ https://ncbi.nlm.nih.gov/pubmed/20808239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/RLI.0b013e3181ed1b3b |
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