A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI

Human and murine cerebral malaria are associated with elevated levels of cytokines in the brain and adherence of platelets to the microvasculature. Here we demonstrated that the accumulation of platelets in the brain microvasculature can be detected with MRI, using what we believe to be a novel cont...

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Détails bibliographiques
Auteurs principaux: von zur Muhlen, Constantin, Sibson, Nicola R., Peter, Karlheinz, Campbell, Sandra J., Wilainam, Panop, Grau, Georges E., Bode, Christoph, Choudhury, Robin P., Anthony, Daniel C.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2008
Sujets:
Technical Advance
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242620/
https://ncbi.nlm.nih.gov/pubmed/18274670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33314
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