Visualization of Activated Platelets by Targeted Magnetic Resonance Imaging Utilizing Conformation-Specific Antibodies against Glycoprotein IIb/IIIa

Ruptured atherosclerotic plaques, lined with activated platelets, constitute an attractive target for magnetic resonance imaging (MRI). This study evaluated whether microparticles of iron oxide (MPIO) targeting ligand-induced binding sites (LIBS) on the activated conformation of glycoprotein IIb/III...

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Hlavní autoři: von zur Muhlen, Constantin, Peter, Karlheinz, Ali, Ziad A., Schneider, Jürgen E., McAteer, Martina A., Neubauer, Stefan, Channon, Keith M., Bode, Christoph, Choudhury, Robin P.
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2009
Témata:
Methods in Vascular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914450/
https://ncbi.nlm.nih.gov/pubmed/18515970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000135660
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