Glc-6-PD and PKG contribute to hypoxia-induced decrease in smooth muscle cell contractile phenotype proteins in pulmonary artery

Persistent hypoxic pulmonary vasoconstriction (HPV) plays a significant role in the pathogenesis of pulmonary hypertension, which is an emerging clinical problem around the world. We recently showed that hypoxia-induced activation of glucose-6-phosphate dehydrogenase (Glc-6-PD) in pulmonary artery s...

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Huvudupphovsmän: Chettimada, Sukrutha, Rawat, Dhwajbahadur K., Dey, Nupur, Kobelja, Robert, Simms, Zachary, Wolin, Michael S., Lincoln, Thomas M., Gupte, Sachin A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2012
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426433/
https://ncbi.nlm.nih.gov/pubmed/22582112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00002.2012
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