Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension

Increased cell proliferation and migration, of several cell types are key components of vascular remodeling observed in pulmonary hypertension (PH). Our previous data demonstrate that adventitial fibroblasts isolated from pulmonary arteries of chronically hypoxic hypertensive calves (termed PH-Fibs)...

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Autors principals: Anwar, Adil, Li, Min, Frid, Maria G., Kumar, Binod, Gerasimovskaya, Evgenia V., Riddle, Suzette R., McKeon, B. Alexandre, Thukaram, Roopa, Meyrick, Barbara O., Fini, Mehdi A., Stenmark, Kurt R.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426432/
https://ncbi.nlm.nih.gov/pubmed/22582113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00050.2012
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