PI3K, Rho, and ROCK play a key role in hypoxia-induced ATP release and ATP-stimulated angiogenic responses in pulmonary artery vasa vasorum endothelial cells

We recently reported that vasa vasorum expansion occurs in the pulmonary artery (PA) adventitia of chronically hypoxic animals and that extracellular ATP is a pro-angiogenic factor for isolated vasa vasorum endothelial cells (VVEC). However, the sources of extracellular ATP in the PA vascular wall,...

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Detalhes bibliográficos
Main Authors: Woodward, Heather N., Anwar, Adil, Riddle, Suzette, Taraseviciene-Stewart, Laimute, Fragoso, Miguel, Stenmark, Kurt R., Gerasimovskaya, Evgenia V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777489/
https://ncbi.nlm.nih.gov/pubmed/19684203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00038.2009
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